The IGF-1 (Insulin Growth Factor
1) is a hormone produced naturally in the human body.
It’s primary function is to promote growth and development of cells. There are two types of IGF-1; Insulin-like Growth Factors (IGF) and Growth Hormone Binding Protein 3 (GHRP). Both have been shown to play important roles in regulating cell proliferation, differentiation, survival, maturation, migration and angiogenesis.
In addition to its role in promoting growth and development, IGF-1 has been shown to influence many physiological processes such as bone mineralization, wound healing, immune system activation and neuroendocrine functions. IGF-1 has also been implicated in cancer prevention through inhibition of tumor initiation or promotion. The mechanisms by which IGF-1 exerts these effects remain unclear. However, it appears that IGF-1 may act directly on target genes or indirectly via other signaling pathways.
IGF-1 is synthesized primarily from cholesterol and free fatty acids in the liver, but also occurs in muscle tissue. Levels increase with age, particularly after puberty. These increases persist into adulthood and reach their peak during childhood and adolescence. After puberty, IGF-1 levels decrease rapidly with no further changes until menopause when they begin to rise again. The exact mechanism by which this happens remains unknown.
It is important to note that the vast majority of IGF-1 in the blood is bound to at least one of its binding proteins (IGFBPs) which limits its availability for biological activity. There are six IGFBPs that are produced by the liver and other tissues, each with specific affinity towards IGF-1 and IGF-
2. The most prominent of these proteins, IGFBP-3 has a 10-100x greater affinity for IGF-1 than for IGF-2.
IGF-1 has been found to be effective in the treatment of burns, bone disorders, congestive heart failure, diabetes, and several types of cancer. It has also shown antirenoceptive effects and can reduce or even eliminate opioids required for pain therapy. The studies that have been done, however have been limited to mice and rat models. No human trials have yet been done.
IGF-1 is not a readily available drug, and is therefore only available through private medical suppliers. It is most commonly available in a liquid form, and must be frozen continually to ensure its stability. It is usually dosed subcutaneously (under the skin), a method that involves pinching the skin in several places to allow access to a small amount of liquid, which is then inserted under the skin with an insulin syringe.
The average cost of IGF-1 is $10,000 for a six month supply, making it an extremely expensive drug. A cheaper method of delivery involves the intramuscular (into the muscle) injection of growth hormone releasing factors (GHRFs), which stimulate the natural release of growth hormone. This method however, frequently leads to side effects such as pain in the joints and tendons, dizziness, headaches, and nausea.
The primary use of IGF-1 is for the promotion of growth in pediatric patients. Other uses for the drug are still being explored. The IGF-1 is then usually dosed every day or several times a week to maintain stable blood levels. This method is usually only effective for about two years, at which point the endogenous release of growth hormone decreases and the use of GHRFs must be increased or replaced with anabolic steroids. It’s not currently known if IGF-1 has any beneficial effects in healthy adults.
I have been diagnosed with growth hormone deficiency (GHD), and I want to start IGF-1 therapy.
This is a complicated question that is best directed to your personal physician. He or she will have to contact an endocrinologist or other physician who is qualified to prescribe this medication. This can also lead to an increase in muscle growth and anabolism when used in conjunction with anabolic steroids.
There are several side effects associated with the use of IGF-1, many of which can be quite serious. The most commonly known effect is a slowing of the user’s aging process. Almost all IGF-1 users report a general feeling of well being and a slowing down of the effects of aging.
Is IGF-1 Legal?
The only FDA approved indication for IGF-1 is for the treatment of GHD. It is illegal for any other use at this time.
What do you recommend as the best method of intake?
The subcutaneous (under the skin) injection of recombinant growth hormone is extremely effective. This is the most commonly used method of dosing, and has very few side effects. Hair loss is also reported to stop, or even grow back, though this is not universal.
Other effects of IGF-1 can be quite serious, and even fatal in some cases. IGF-1 has been shown to cause the growth of cancerous cells at several cancer research centers. The effect is amplified when IGF-1 is used in conjunction with anabolic steroids and testosterone.
How is the best way to store IGF-1?
It is recommended that all growth hormones be kept in the freezer. It is important that IGF-1 not be frozen, as freezing can destroy its effectiveness. A constant temperature of around 68 degrees is best.
Is there a breeding effect with IGF-1?
The use of IGF-1 has been known to increase the number of healthy and strong births among women who use it for fertility treatments. This does not mean that it will definitely cause cancer in every user, but it is certainly a risk that should not be taken. It has also been linked to causing severe heart and liver damage. It is believed that IGF-1 increases fertility in women.
What is the IGF-1 half-life?
The half-life of most growth hormones is between one and two hours, depending on the hormone. It is very important to remember this when dosing, as even the smallest miscalculation can lead to devastating health problems or even death.
How long does it take for IGF-1 to start working?
In fact, the human liver can only process a finite amount of IGF-1 per day.
IGF-1 can take several weeks to start working, as the human body does not immediately accept the IGF-1 infused into it. It is important that one be patient, as immediate changes are unlikely, and could be dangerous. IGF-1 should not be taken for less than six months without the guidance of a physician.
What is the most important information I should know about IGF-1?
This amount is different for each person. As such, IGF-1 should not be taken at the same time every day. Instead, the best practice is to take IGF-1 at different intervals for each dosage.
What are the possible side effects of IGF-1 usage?
There are very few side effects of IGF-1 alone. The drug has been shown to cause cancer in some patients, as well as other serious and even fatal conditions.
As with most pharmaceuticals, IGF-1 will not improve the intelligence of a person. Customers who are expecting immediate and radical changes in their child’s school performance or behavior, for instance, may be disappointed. That being said, many parents have noted that over the long term their children seem to become smarter and stronger, and are more likely to succeed in life.
People with cancer should not take this drug. It is, as of current research, impossible to predict who will be effected in this way.
What does IGF-1 do?
Insulin-like growth factor is a naturally occurring hormone in the human body. It causes cell division, which allows human beings to grow. The IGF-1 that we use is natural, and merely introduces an additional amount of IGF-1 into the human body. This additional amount causes healthy muscle growth, drastically increases strength, and even has a positive effect on the intelligence of a user.
Does IGF-1 come in pills, injections, or other forms?
IGF-1 is only available in injectable form, as this is the only true way to ensure that the human body receives a consistent amount of IGF-1. Pills would be crushed and destroyed in the digestive system, and other delivery methods such as patches simply have not been effective at delivering IGF-1 in a useful way.
IGF-1 is usually injected into users once a day. The amount of IGF-1 in each dose must be carefully measured out, as the human liver can only process a certain amount per day.
Are there any precautions that should be taken before starting on IGF-1?
Yes, there are several tests that should be done before beginning treatment with IGF-1. The most important is a cancer test.
Does IGF-1 come in strengths?
Yes, IGF-1 comes in five strengths: 0.1mg, 0.2mg, 0.5mg, 1mg, and 2mg. The smallest strength is 0.1mg, and the largest strength is 2mg. Most people start on either the 0.2mg or 0.5mg level when they begin using IGF-1 for the first time. Existing cancer cells are extremely sensitive to IGF-1, and giving additional IGF-1 to a cancer patient could cause the cells to divide and grow at an alarming rate. As such, anyone who knows they have cancer or has a history of cancer in their family should not take IGF-1 for any reason.
Another precaution is a simple blood test that can determine how much IGF-1 your liver can process per day.
Is IGF-1 approved by the FDA?
Insulin-like growth factor has been shown in several studies to be safe for human use, and is widely used across the world. It is not approved by the FDA because it is a naturally occurring hormone, not a drug.
For this reason, it can not be purchased in stores or online, and can only be acquired through private prescription. A physician must write out a prescription before a patient may begin treatment with IGF-1. Different people can process different amounts of IGF-1 safely. If you have any reason to believe that you may be unable to process larger amounts of IGF-1, it is extremely important that you speak with your doctor before beginning treatment.
A final precaution is pregnancy. Any woman who is even possibly pregnant should not take IGF-1. There have been no tests done on the effects of IGF-1 on a fetus, so any exposure could be extremely dangerous.
How is IGF-1 different from steroids or other muscle-building drugs?
Insulin-like growth factor is different from most other muscle-building drugs on the market today. It is natural for the human body and does not get filtered out by the liver like other supplements such as creatine, and therefore has a much lower chance of causing damage to internal organs such as the liver.
What kind of results can I expect from IGF-1?
IGF-1 can be used for three main reasons: muscle growth, strength increase, and recovery improvement. These three things all depend on the body of the user as well as the amount of IGF-1 they take. As such, it is impossible to say how much you will gain from IGF-1. It is absolutely true that IGF-1 is extremely effective at helping the body build muscle and increase strength. It has a extremely low chance of causing cancer due to its natural origins within the human body. It also has a very low risk of causing allergic reactions, as IGF-1 is broken down differently by the body than other supplements which can cause allergic reactions in some people. Finally, it does not have any of the negative social connotations that anabolic steroids have, and therefore athletes and bodybuilders often prefer to use IGF-1 instead.
Does IGF-1 have any bad side effects?
For those who already have a high level of muscle mass, IGF-1 should mainly be used to improve recovery. This is because the added recovery benefits will be more noticeable on someone with a higher level of muscle mass. People with low levels of muscle mass may not notice much difference in recovery at lower dosages of IGF-1.
The most important thing to remember about IGF-1 is that the effects are not immediate.
The only major side effect of IGF-1 that has been proven to the date is that it can increase insulin levels in some patients. For this reason, it is recommended to not use IGF-1 if you are diabetic or have a family history of diabetes. It is extremely important to remember that any changes in your health conditions can still occur while using IGF-1, you just may notice them at different times. Just because IGF-1 is highly anabolic (muscle building) and shows great promise in clinical studies, that does not mean you will definitely begin gaining muscle at an enhanced rate. The IGF-1 must be taken over a long period of time (at least several months) for the effects to build up and for you to see any major changes.
It is also extremely important to stay hydrated when using IGF-1.
How do I take IGF-1 and how much does it cost?
Before purchasing any IGF-1, be sure to speak with a physician. Your doctor may have specific instructions on how to take IGF-1, depending on your age, weight, health conditions, and other factors. Each vial of Humatrope contains 100mcg of IGF-1 (100 doses per vial).
Insulin-like growth factor is not like most muscle-building drugs, where you take it and immediately begin to notice a change in size. IGF-1, instead, is something you have to use on a long-term basis before you really see any major changes in your body composition.
Most people who use IGF-1 only use it for a short period of time. The first step in taking IGF-1 is to draw up the desired amount using the medical insulin syringe that should have come with the IGF-1. Insulin syringes are measured in units; the Humatrope IGF-1 comes in a 10 unit per mL strength, so you will need to draw up 10 units of IGF-1 for every 1mL of liquid.
Step 1: Draw up 10 units of Humatrope into the medical insulin syringe. This is because the cost of the drug is extremely high.
Step 2: Invert the syringe and tap the side gently to make sure you have gotten all of the IGF-1 into the barrel of the syringe.
Step 3: Push the plunger down SLOWLY to draw the air into the barrel, followed by a small amount of the IGF-1. Air is drawn into the barrel first so that upon injection, there is less chance of getting an air bubble caught in your skin, which could lead to an abscess.
Step 2: Pull back the plunger on the syringe to draw the correct amount of fluid. It is extremely important to make sure you get the correct measurement, as IGF-1 is extremely pure and extremely potent. If you put in too much, you could overdose and have serious health complications.
Step 3: Inject the liquid into your subcutaneous fat layer. This is the layer of fat that lies right below your skin.
Step 4: Hold the syringe at a 90 degree angle to your skin, and inject the IGF-1 into either your stomach, glutes (buttocks), or the top of your thighs. Injecting the IGF-1 too close to your joints can cause problems with swelling and pain, so be sure to stay at least 2 inches away from your ankles and knees when injecting.
Alternatively, you can also mix the IGF-1 with any drink that isn’t alcohol. The most common places to inject are either the sides or backs of your thighs and your stomach area, although there are other parts of your body that can be injected into as well.
Step 4: If you choose, and many people do, you may wrap your injection sight in a bandage to help prevent irritation at the injection sight. Alcohol is bad for IGF-1, so never drink alcohol if you have IGF-1 in your stomach.
It is extremely important to follow the correct dosages below when using IGF-1, as it is extremely potent and overdoses can lead to serious medical issues.
For a beginner, the best way to use Humatrope is to take 0.1mL of Humatrope per 1kg of bodyweight.
Step 5: Go onto injections 2, 3 and 4. Injections 2 through 4 should be done at least 48 hours after the first injection in order to give your body time to recover and rest before taking IGF-1 again.
Step 6: After 48 hours, you may remove the bandage if you have been injecting into your thighs or stomach. If you have been injecting into the back of your thighs, leave the bandage on for another 24 hours. This can either be split into 2 daily injections of 0.05mL per 1kg of bodyweight, or one injection of 0.2mL per 1kg of bodyweight.
It is recommended that you use the split dosage over a double dosage, as there is less risk of medical complications at this level and more IGF-1 will remain active in your body.
Step 7: You may now go onto injections 5, 6 and 7, which should be at least 48 hours after the second injection.
If you have been injecting into your stomach area, you need to wait at least 72 hours before taking a double dosage.
Step 7: Continue this routine every 48-72 hours for as long as you would like to continue using IGF-1. After your last injection, it is recommended that you do not have another injection for at least 2 days.
So, as you can see, the Humatrope Insulin-Like Growth Factor 1 is a very intensive substance to use. It requires maintenance, care and dedication if used correctly.
If you have any questions about how to use Humatrope, always consult your physician first. Take at least 2 days off before using IGF-1 again, and take a week off after every 8-week period of usage.
If you are using the subcutaneous method, follow these instructions:
Step 1: Choose where you would like to inject. If you have sensitive skin, it is recommended that you do not inject into your stomach, but instead the back of your thighs.
Buy Humatropin 10iu Online
Humatrope is a pharmaceutical drug that has the ability to increase levels of Insulin-Like Growth Factor 1 in your body, making it an extremely useful drug for people who are suffering from conditions that have IGF-1 as a cause. It is most commonly used to treat children and adults who are experiencing growth issues, or for people who have suffered an injury which prevents them from healing properly. If you do not have sensitive skin, it is up to you where you would like to inject. If you decide to inject into your stomach, be sure that the skin is not sucked in and ensure that there are no hairs in this area as this will cause irritation and create small, hard lumps under the skin.
If you choose to inject anywhere else, make sure the area is clean and free of hair.
Humatrope can be purchased online without a prescription.
Humatrope is also used to increase the chance of successful conception for people who are experiencing issues with fertility due to low IGF-1 levels in the body. For females, it is most effective when used while trying to conceive. For males, it is most effective when used shortly before having sexual relations with a female who is trying to conceive. This drug should not be mixed with other fertility drugs or remedies. Make sure that the needle is sharp enough to pierce the skin and that you rub the area for at least a minute to ensure that the temperature of the skin and the liquid are even.
If not, this may cause the liquid to clump and this could block your veins if you do not take proper care.
Humatrope works by increasing your body’s own natural production of IGF-1. Speak to your physician about the correct dosages and methods of use.
Humatrope can be injected subcutaneously, intramuscularly, or intravenously depending on what the patient needs. The length of time that it takes for the effects of Humatrope to begin are different for everyone. It is a fast-acting drug that increases the level in your blood by up to 500% in just a few hours. The effects begin to wear off after about 3 days but it is recommended that you only use the drug for 3 days at a time so as to not disrupt your body’s natural IGF-1 levels and to allow it to replenish.
After the 3 days, your IGF-1 levels should be back to normal with no adverse effects on your body. For some people, it is effective almost immediately after injection. For others, it takes a few days for IGF-1 levels to increase to adequate amounts for the drug to take effect.
Insulin-like growth factor 1 (IGF-1) is a protein hormone that is naturally created in the human body. It is produced by the liver and helps control levels of sugars and other nutrients in the blood. It also plays a large role in cell division and growth.
If you have any questions about how to use Humatrope, ask your physician first before using it.
When someone has low IGF-1 levels in their body, it can cause an issue with proper growth and development. It can also cause issues with proper healing of wounds and injuries and can prevent the body’s ability to heal itself naturally.
Humatrope is a drug that is used to increase the amount of IGF-1 in your body by giving you injections of the drug. This helps the body to heal properly from wounds and increases the rate of cell division.
Warning : Humatrope should never be injected into a vein or artery.
Normally, the drug is available in vials of 10mcg/0.3mL formulations of the dry powder and ready-made liquid, but other sizes are also available on the market. The liquid is normally supplied in vials containing 10 or 20 mL of liquid.
The proper dose is based on your height, weight, age, and other health-related factors. Your physician will decide what is the right dose for you.
These are the most common adverse effects of Humatrope, but they do not include all possible effects. If you notice any severe reactions or other effects while taking this drug, inform your physician immediately. Any of these factors can cause changes in the dose that you will need and if you have any of these conditions, you may require a different dose than other people.
Humatrope is most commonly injected subcutaneously (under the skin), intramuscularly (in the muscle), or intravenously (in a vein).
How should I store this drug?
Although Humatrope is a self-contained injectable that does not require additional tools for its administration, you should keep it in a safe place away from children and pets.
The drug should be kept in a cool, dry place where it is protected from sunlight, but it should not be kept in the refrigerator. Humatrope should be kept out of the reach of children and pets since it is a potent drug.
In addition to the dry powder and liquid formulations of Humatrope, it is also available in a ready-to-use solution. This formulation is normally supplied in a vial that contains 10 or 20 mL of solution and should be stored in a refrigerator at all times. The vial should be kept safely away from children and pets.
Humatrope is one of the most well-known growth hormone drugs used for treatment of growth issues. It is a man-made form of the growth hormone that is normally produced by the human pituitary gland.
This drug is used to treat children and adults with growth problems related to hormonal issues.
It should not be used to treat growth problems caused by emotional, environmental, or dietary issues. It is a well studied drug with an excellent safety profile and a large body of clinical trials that support its use.
HGH is often used to treat children that do not grow properly, but it can also be used in adults. When used for children, it can greatly increase the rate of growth and development in addition to increasing the child’s stature. When used for adolescents and adults, it can reverse the effects of Aging. It is a safe drug as long as it is used correctly. If you have any questions about this drug, ask your physician or pharmacist before using it.
Humatrope (somatropin) is not a steroid and it is approved by the US Food and Drug Administration for the treatment of growth disorders. It is a 191-amino acid protein similar to human growth hormone produced naturally by the body. The average growth hormone molecule is extremely large, so the drug is manufactured using a genetically altered E. coli bacteria to create smaller copies of the hormone (somatropin).
Humatrope (somatropin) is an expensive drug and has been approved for reimbursement by most health insurance plans. The price of this drug is outrageous and this is why a lot of people are seeking a Humatrope Discount Card because they simply cannot afford the high standard price for this medication. Each vial contains 10 milligrams (10mg) of somatropin.
A Humatrope Discount Card can save you a lot of money on the price of this medication. The manufacturers of somatropins are making so much money on these drugs that they can easily afford to discount them, but they choose not to since it makes more profit for them in the long run to charge the outrageous price for this drug.
A Humatrope Discount Card can get up to 30% off the List Price. A 30% discount equals an average savings of $1,200 per year for those who are paying the highest retail price for somatropin.
A lot of insurance plans will not cover this drug. Most will only cover a one or two month supply and only after a very expensive copay. This means that it can cost a lot of money out of pocket even with a discount card and that’s why many people are seeking out cheaper alternatives such as biosimilars.
Sources & references used in this article:
Growth and Longevity: The Enigma and Potential of IGF-1 by A Eriksson – breakingmuscle.com
Aging and longevity: the IGF-1 enigma by P Anversa – 2005 – Am Heart Assoc
How does suppression of IGF-1 signaling by DNA damage affect aging and longevity? by G Hinkal, LA Donehower – Mechanisms of ageing and development, 2008 – Elsevier
The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of Alzheimer’s disease: from model organisms to human disease by S Freude, K Schilbach… – Current Alzheimer …, 2009 – ingentaconnect.com
Age-dependent impairment of endothelial progenitor cells is corrected by growth hormone mediated increase of insulin-like growth factor-1 by T Thum, S Hoeber, S Froese, I Klink… – Circulation …, 2007 – Am Heart Assoc
The insulin-like growth factor I system: physiological and pathophysiological implication in cardiovascular diseases associated with metabolic syndrome by J Ren, P Anversa – Biochemical pharmacology, 2015 – Elsevier